HORDB

ID: hor000816
Uniprot ID: Q86N75
Protein name: Corazonin precursor-related peptide
Gene name: crz
Organism: Bombyx mori (Silk moth)
Family: Corazonin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Bombyx (genus), Bombycinae (subfamily), Bombycidae (family), Bombycoidea (superfamily), Obtectomera, Ditrysia, Heteroneura (parvorder), Neolepidoptera (infraorder), Glossata (suborder), Lepidoptera (order), Amphiesmenoptera (superorder), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity; GO:0071858 corazonin receptor binding
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0045823 positive regulation of heart contraction
GO CC: GO:0005576 extracellular region

Sequence: DGHKRDELRDEVLERILTPCQLDKLKYVLEGKPLNDRLFVPCDYIEEEVNQPKRYKGERNHELFDVFQ
Length: 68(34-101)
Propeptide: MVTNITLILTLMTLASVTAQTFQYSRGWTNGKRDGHKRDELRDEVLERILTPCQLDKLKYVLEGKPLNDRLFVPCDYIEEEVNQPKRYKGERNHELFDVFQ
Signal peptide: MVTNITLILTLMTLASVTA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000816_AF2.pdb

hor000816_ESM.pdb

Mass:	942657	Formula:	C365H574N102O111S2
Absent amino acids:	AMSW	Common amino acids:	EL
pI:	4.87	Basic residues:	14
Polar residues:	12	Hydrophobic residues:	19
Hydrophobicity:	-100.59	Boman Index:	-20536
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	84.41
Instability Index:	4165.15	Extinction Coefficient cystines:	4595
Absorbance 280nm:	68.58